PASSPORT

In 2006, over 45.000 European citizens died of cirrhosis of the liver and 44,000 additional citizens of liver cancer, knowing that the same year 48,700 new liver cancer cases were declared. Surgical procedures remain the options that offer the foremost success rate against such pathologies. Regretfully, surgery is not so frequent due to several limitations.

Indeed, eligibility for liver surgery is based on the minimum safety liver volume remaining after resection (standardized FLR), but this minimum value varies over time and from one patient to another according to biological and mechanical properties of the liver. Since 1996, a large set of preoperative planning software has been developed, but all of them provide only the volume of the liver before and after resection. However interesting, this limited information is not sufficient to improve the rate of surgical eligibility.

PASSPORT for Liver Surgery (PAtient specific simulation and preoperative realistic training for liver surgery) project aims at overcoming these limitations by offering a patient-specific modelling that combines anatomical, mechanical, appearance and biological preoperative modelled information in a unified model of the patient. This first complete "Virtual liver" will be developed in an Open Source Framework allowing vertical integration of biomedical data, from macroscopic to microscopic patient information.

From these models, a dynamic liver modelling will provide the patient-specific minimum safety standardized FLR in an educative and preoperative planning simulator allowing to predict the feasibility of the gesture and surgeons' ability to realise it. Thus, any patient will be able to know the risk level of a proposed therapy.

The propsed project expects to increase the rate of surgical treatment so as to save patients with a liver pathology. To reach these purposes, PASSPORT is composed of a high level partnership between internationally renowned surgical teams, leading European research teams in surgical simulation and an international leading company in surgical instrumentation.

For further information, please visit:
http://www.passport-liver.eu

Project co-ordinator:
Institut de Recherche contre les Cancers de l'Appareil Digestif (France)

Partners:

  • Universität Leipzig (Germany)
  • Technischen Universität München (Germany)
  • University College London (United Kingdom)
  • Imperial College of Science, Technology and Medicine (United Kingdom)
  • Karl Storz GmbH & Co. KG (Germany)
  • Université Louis-Pasteur (France)
  • Institut National de Recherche en Informatique et en Automatique (France)
  • Eidgenössische Technische Hochschule Zürich (Switzerland)
  • Université catholique de Louvain (Belgium)

Timetable: from 06/2008 - to 05/2011

Total cost: € 5.460.000

EC funding: € 3.640.000

Programme Acronym: FP7-ICT

Subprogramme Area: Virtual physiological human

Contract type: Collaborative project (generic)

Most Popular Now

Artificial Intelligence Predicts Dementi…

Imagine if doctors could determine, many years in advance, who is likely to develop dementia. Such prognostic capabilities would give patients and their families time to plan and manage treatment...

Using Machine Learning to Improve Patien…

Doctors are often deluged by signals from charts, test results, and other metrics to keep track of. It can be difficult to integrate and monitor all of these data for...

Researchers Uncover Security Issues with…

Use caution when entering personal health information into a convenient app on your mobile device, because not all apps are created equal when it comes to protecting your privacy, warns...

Self-Powered Paper-Based 'SPEDs' may Lea…

A new medical-diagnostic device made out of paper detects biomarkers and identifies diseases by performing electrochemical analyses - powered only by the user's touch - and reads out the color-coded...

New App Uses Smartphone Selfies to Scree…

Pancreatic cancer has one of the worst prognoses - with a five-year survival rate of 9 percent - in part because there are no telltale symptoms or non-invasive screening tools...

Nurses Becoming e-Nurses by Using Patien…

The ambitions of NHS Digital’s e-nursing week and the Royal College of Nursing's (RCN) 'Every nurse an e-nurse' campaign are being realised by nurses across the UK, who are seeing...

New Diagnostic Tool Spots First Signs of…

Researchers have developed the first tool that can diagnose Parkinson's disease when there are no physical symptoms, offering hope for more effective treatment of the condition. There are currently no...

Stroke Patient Improvement with a Brain-…

University of Adelaide researchers have shown that it is possible for stroke patients to improve motor function using special training involving connecting brain signals with a computer. In a "proof-of-principle...

eHealth Hub Call: Lean Startup Academy

The Lean Startup Academy is an unique opportunity to mature your business by systematically testing your ideas against the market with the support of experts. The course will help you...

Google Glass App Helps Autistic Children…

A prototype software application, to be used with the optical head-mounted display Google Glass, has been designed as a social-skills coach for children with autism spectrum disorder (ASD). A new...

Philips Innovations at IFA 2017 Put Cons…

At this year's Internationale Funkausstellung (IFA) in Berlin, Germany, Royal Philips (NYSE: PHG, AEX: PHIA) showcases new products and services that empower consumers to take an active role in managing...