SIMAP

SIMAP will develop a simulation model of the cancer related MAP-kinase pathway, integrating and analyzing data from various types of resources, which may assist in the development of better cancer treatment.

The completion of the human genome gave hope for a new age of medical understanding, but 4-5 years later costs of drug development are still rising and the success rate has not improved. Drugs that have already hit the market are found to have major side effects not perceived in the past and are often given to patients without discrimination on their likeliness to respond.

Large scale methodologies that thrive in recent years, allowed the industry and academia to gather more information on RNAs and proteins. However, the understanding of the molecular and cellular processes is still lacking, not to mention the connection to the clinical outcome. In order to fully use this data, a comprehensive integration and modelling effort is needed. A systematic rational hypothesis-driven research approach connecting all those levels of information is a much needed computational tool. This is the main goal of SIMAP project.

The ultimate goal of SIMAP is to develop a comprehensive simulation biochemical model of EGFRMAP kinase pathway in connection to cancer clinical information. SIMAP will:

  • Incorporate low-level biochemical modelling of individual molecules;
  • Simulate the behaviour of the pathway;
  • Add genomic and proteomic data;
  • Incorporate individual patients’ responses; and
  • Analyze sub population of responses in the context of the biochemical behaviour and genotype data

For further information, please visit:
http://www.simap-project.org

Project co-ordinator:
Compugen Ltd.

Partners:

  • Aureus Pharma, (FR)
  • Compugen Ltd., (IL)
  • Consejo Superior de Investigaciones Científicas, (ES)
  • Halevi Dweck & Co.Arttic Israel Company Ltd., (IL)
  • Fundacio Institut De Recerca De L'Hospital Universitari Vall D'Hebron, (ES)
  • Fondazione IRCCS Istituto Nazionale Dei Tumori, (IT)
  • The Max-Planck Institute for Infection Biology, (DE)
  • The University of Glasgow, (UK)
  • The Weizmann Institute of Science, (IL)

Timetable: from 01/06 – to 12/08

Total cost: € 4.464.201

EC funding: € 3.126.662

Instrument: STREP

Project Identifier: IST-2004-027265

Source: FP6 eHealth Portfolio of Projects

Most Popular Now

Augmented Reality Visor to Dramatically …

Employing new photonics technology, European scientists are developing a new Augmented Reality surgical visor in a bid to improve accuracy of interventions, showing anaesthetic and medical data while superimposing a...

Read more

Interactive Health Apps May Inspire Heal…

Just like real doctors and nurses, online health tools with good - but controlled - communication skills can promote healthier lifestyles, according to researchers. However, if their tone is conversational...

Read more

Call for Papers: EHB 2017 - IEEE Interna…

22 - 24 June 2017, Sinaia, Romania. The 6-th edition of the International Conference on e-Health and Bioengineering, EHB 2017, will take place in the city of Sinaia, Romania. This year...

Read more

UK and Italian Health Tech Firms to Help…

Data sharing ambitions set out in newly published sustainability and transformation plans (STPs) have been given a boost by a new strategic partnership between data management specialist Stalis and Italy's...

Read more

From Health Apps to Nursing Robots - A G…

25 - 27 April 2017, Berlin, Germany. Around the world the subject of e-Health is steadily gaining in importance, whether it involves electronic patient files, online video consultations or any of...

Read more

Philips Teams Up with German Startup One…

Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, today announced a partnership agreement with German digital health company Onelife Health to jointly develop innovative connected health...

Read more

EU eHealth Competition 2017

The eHealth Competition is an initiative that rewards the best eHealth / mHealth solutions produced by European SMEs (Small and Medium Enterprises). Its objective is to support business success of...

Read more

Philips and LabPON Plan to Create World…

Royal Philips (NYSE: PHG, AEX: PHIA) and LabPON, the first clinical laboratory to transition to 100% histopathology digital diagnosis, have announced its plans to create a digital database of massive...

Read more

Virtual Reality Cognitive Training Game …

Greek researchers demonstrated the potential of a self-administered virtual supermarket cognitive training game for remotely detecting mild cognitive impairment (MCI), without the need for an examiner, among a sample of...

Read more

Technology Boost for Health and Social C…

Health and social care organisations aiming to be fully compliant with the government’s Personalised Health and Care 2020 plan, can now access electronic health record (EHR) and healthcare integration technologies...

Read more

Agfa HealthCare's Health Management Pla…

Agfa HealthCare announces today that its health management platform, including the XERO universal image viewer, has been selected to support the joint Radiotherapy Treatment Project of the Saolta University Health...

Read more

Philips Introduces Advanced Radiology So…

Royal Philips (NYSE: PHG, AEX: PHIA), a global leader in health technology, has unveiled new advanced radiology solutions at the 2017 European Congress of Radiology (ECR). In response to today's...

Read more
(HEALTH IT) SPACE - Take a look at who has just Joined