Philips-Sponsored Clinical Study Demonstrates Significant Breakthrough for COPD Treatment

PhilipsRecently published advancements in pulmonary research suggest that the combination of non-invasive ventilation (NIV) and home oxygen therapy (HOT) can significantly prolong time to readmission or death for patients with chronic obstructive pulmonary disease (COPD) following a life-threatening respiratory event or exacerbation. The five-year, multi-center study resulted in prolonged median time to readmission or death by nearly three months, and improved patient health-related quality of life in the first six weeks.

"Patients with severe COPD and persistent hypercapnia have historically had limited therapy options available to them and outcomes have generally been poor," said Dr. Nicholas Hart, Professor and Clinical Director of Lane Fox Respiratory Service, St Thomas’ Hospital in London. "The trial suggests that combining home oxygen and home non-invasive ventilation therapy can reduce hospital readmissions while maintaining patients’ quality of life, which will drastically change the way we approach COPD treatment worldwide. We are looking forward to hopefully decreasing the mortality and readmission rates that result from severe COPD with further research."

The randomized clinical trial of 116 patients in the United Kingdom was co-sponsored by Royal Philips (NYSE: PHG; AEX: PHIA) and carried out by respiratory experts at St Thomas' Hospital in London. The results showed that the addition of home NIV prolonged the median time to readmission or death from 1.4 months to 4.3 months.

"This study shows that home noninvasive ventilation is a potent, therapeutic tool that clinicians can use to help keep patients with advanced COPD out of the hospital," said Dr. Teofilo Lee-Chiong Jr., Chief Medical Liaison at Philips. "We hope that this will, in turn, allow them to lead healthier and more active lives at home. These findings add considerably to our knowledge of this highly prevalent and debilitating respiratory disorder, and are expected to greatly influence how clinicians care for patients with COPD on long-term oxygen therapy."

Preliminary results from this trial were announced in September 2016 at the European Respiratory Society's International Congress in London, U.K. The final paper, entitled 'Effect of home non-invasive ventilation with oxygen therapy vs. oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: A randomized clinical trial', was published in the Journal of the American Medical Association after being presented at the American Thoracic Society International Conference (Washington DC, US, May 19 - 24).

In April 2017, another Philips-sponsored study demonstrated significant cost savings for payers and hospitals from reduced COPD readmission rates resulting from a multifaceted care program that included the use of AVAPS-AE, a proprietary mode of non-invasive ventilation in the Trilogy device. Philips' sponsorship of these studies is the latest in the company's continued commitment to pioneering the development of home NIV technologies and ultimately help COPD patients breathe easier.

Philips works every day to support COPD patients and help them improve their quality of life by offering a range of solutions, including advanced NIV therapies such as the DreamStation BiPAP AVAPS and S/T, BiPAP A40 (available outside the United States) and Trilogy. Today, Philips is enabling more efficient patient management with the expansion of its connected Trilogy and Care Orchestrator, now commercially available in North America. For additional information on Philips' solutions for sleep and respiratory care, follow @PhilipsResp or visit www.respironics.com.

About Royal Philips
Royal Philips (NYSE: PHG, AEX: PHIA) is a leading health technology company focused on improving people's health and enabling better outcomes across the health continuum from healthy living and prevention, to diagnosis, treatment and home care. Philips leverages advanced technology and deep clinical and consumer insights to deliver integrated solutions. Headquartered in the Netherlands, the company is a leader in diagnostic imaging, image-guided therapy, patient monitoring and health informatics, as well as in consumer health and home care. Philips' health technology portfolio generated 2016 sales of EUR 17.4 billion and employs approximately 70,000 employees with sales and services in more than 100 countries.

Most Popular Now

The Digital Revolution in Medicine is Ta…

13 - 16 November 2017, Düsseldorf, Germany. The MEDICA HEALTH IT FORUM at the world’s leading medical trade fair, MEDICA 2017, taking place in Düsseldorf with over 5,000 exhibitors, offers an...

FDA Selects Participants for New Digital…

Today, the U.S. Food and Drug Administration announced the names of the companies selected to participate in a first-of-its kind pilot program that will help revolutionize digital health regulation in...

Future50: Nominate the Top Healthcare IT…

HIMSS Europe has launched Future50 supported by IBM Watson Health, a new flagship initiative that aims to identify and bring together the top 50 leaders in European Healthcare IT in...

Smartphone Apps Launched for Atrial Fibr…

Novel smartphone and tablet applications (apps) for atrial fibrillation patients and healthcare professionals have been launched by heart experts. The objectives and design of the apps are outlined in a...

UBM Strengthens Focus on Medtec Europe f…

17 - 19 April 2018, Stuttgart, Germany. UBM announced today the continuation of its strategy to ensure Medtec Europe is the preeminent, stand alone, European-focussed, medical technology platform by deciding to...

IBM Research and UC San Diego Collaborat…

IBM (NYSE: IBM) and the University of California San Diego have announced a multi-year project to enhance quality of life and independence for aging populations through the new Artificial Intelligence...

Up to $20,000 Available to the Digital H…

MSD is looking for innovators to solve 7 health-related challenges aiming to support physician education or patient disease management. The 3 digital solutions with the most outstanding value will receive...

Wye Valley NHS Trust Goes Live with IMS …

Staff across Wye Valley NHS Trust's four hospitals and community facilities now have a single, shared view of their patients’ records following the deployment of their new electronic patient record...

Online Parent Training Helps Young Kids …

Parents of children with ADHD can feel desperate for resources or treatments to help their children who struggle with inattention, distractibility and impulsiveness affecting school and home. Researchers at Lehigh...

EIT Digital Innovation Activity 'ki elem…

The EIT Digital Innovation Activity 'ki elements' showcases its first prototype called DELTA in Nice at the Institut Claude Pompidou on Innovation Alzheimer Open Day. In the beginning of 2017, EIT...