p-medicine - From Data Sharing and Integration via VPH Models to Personalized Medicine

p-medicine is a 4-year Integrated Project co-funded under the European Community's 7th Framework Programme aiming at developing new tools, IT infrastructure and VPH models to accelerate personalized medicine for the benefit of the patient.

19 project partners from 9 European countries and Japan have dedicated themselves to create support and sustain new knowledge and innovative technologies to overcome current problems in clinical research and pave the way for a more individualized therapy.

Medicine is undergoing a revolution transforming the nature of healthcare from reactive to preventive. This change is catalyzed by a new systems approach which focuses on integrated diagnosis, treatment and prevention of disease in individuals eventually leading to a personalized predictive treatment. p-medicine brings together international leaders in their fields to create an infrastructure that will facilitate this translation from current practice to personalized medicine.

p-medicine project has formulated a coherent, integrated workplan for the design, development, integration of an open, modular framework of tools and services so that p-medicine can be adopted gradually, including efficient secure sharing and handling of large personalized data sets, enabling demanding Virtual Physiological Human (VPH) multiscale simulations (in silico oncology), building standards-compliant tools and models for VPH research, drawing on the VPH Toolkit and providing tools for large-scale, privacy-preserving data and literature mining, a key component of VPH research.

It is understood that privacy, non-discrimination, and access policies are aligned to maximize protection of and benefit to patients. The p-medicine tools and technologies will be validated within the concrete setting of advanced clinical research. Pilot cancer trials have been selected based on clear research objectives, emphasising the need to integrate multilevel datasets, in the domains of Wilms tumour, breast cancer and leukaemia. To sustain a self-supporting infrastructure realistic use cases will be built demonstrating tangible results for clinicians.

For further information, please visit:
http://www.p-medicine.eu

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About p-medicine project
The European Integrated Project p-medicine is supported by the European Commission under the 7th Framework Programme, Grant agreement number 270089.

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